血管性
期限(时间)
辐射
医学
核医学
病理
物理
光学
量子力学
作者
Duane E. Cutright,John M. Brady
出处
期刊:Radiation Research
[BioOne (Radiation Research Society)]
日期:1971-11-01
卷期号:48 (2): 402-402
被引量:28
摘要
Radiation-induced depression of vascularity in the humerus of 62 rats was measured at 2 and 8 months after irradiation with a 250 kVp x-ray unit. These rats were locally irradiated, and later perfused with a silicone rubber material that contained chromium-51. Marked weight loss of the humerus occurred at 8 months with all exposures above 4000 rads. Vascularity decreased in the irradiated humerus to 28% of the unirradiated bone at 4000 rads 2 months after irradiation. At 8 months after irradiation there was no recovery of vascularity at any of the doses studied (2000, 4000, 6000, 8000, and 10,000 rads). The vascular depression after irradiation appeared to consist of two components, the first comprised approximately 70% of the vasculature and was destroyed above 4000 rads. The second, approximately 30% of the vasculature, was present up to 10,000 rads and 8 months after exposure.
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