2019年冠状病毒病(COVID-19)
冠状病毒
严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)
2019-20冠状病毒爆发
倍他科诺病毒
冠状病毒感染
大流行
医学
抗感染药
病毒学
计算生物学
计算机科学
药理学
生物
内科学
传染病(医学专业)
微生物学
疾病
爆发
抗菌剂
作者
Yang Yang,Xiao Cui,Huaying Wei,Caiping Guo,Yulin Zhang
摘要
Abstract: Severe acute respiratory syndrome coronavirus clade 2 (SARS-CoV-2) is an emerging pathogen, which is similar to previous SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV) occurrences. However, we only get few understandings about the pathogenesis of SARS-CoV-2, which need to further be studied. The discovery of an agent that has a treatment efficacy against SARS-CoV-2 is very urgent. In this review, we briefly discuss the virology of this pathogen and focus on the available understanding of the pathogenesis and treatments of this pathogen including the uses of nucleoside analogues, protease inhibitors, interferons, and other small-molecule drugs, on the basis previous comprehensions of SARS and MERS. These reviewed concepts may be beneficial in providing new insights and potential treatments for COVID-19. Keywords: COVID-19, SARS, MERS, virology, pathogenesis, treatment
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