医学
间质性肺病
结缔组织病
肺
氧饱和度
物理疗法
内科学
心脏病学
疾病
有机化学
化学
氧气
自身免疫性疾病
作者
Anuroopa Vijayan,Sakir Ahmed,Sneha Joseph,Aswathy Sukumaran,Subin Ahmed,Padmanabha Shenoy
标识
DOI:10.1136/annrheumdis-2021-220230
摘要
Face masks are a first-line defence against the COVID-19 pandemic.1 Concerns about face masks reducing oxygen saturation (SpO2) have been negated by controlled studies in healthy individuals.2 3 Universal masking must be followed without exceptions. However, persons with pre-existing cardiorespiratory diseases like interstitial lung diseases (ILD) have limited functional reserves. We explored the effects of face masks in patients with connective tissue disease (CTD)-associated ILD (CTD-ILD).
Patients between 18 and 75 years of age with high-resolution CT (HRCT)-proven CTD-ILD and with Medical Research Council scale grades 1–3 dyspnoea and forced vital capacity (FVC) of less than 70% were included in this crossover trial. If FVC was >70%, patients were included only if the extent of involvement on HRCT was more than 20% of the lung. Patients requiring oxygen supplementation and with myositis or lower limb pain were excluded. Initial SpO2 was recorded and a standard 6 min walk test (6MWT) was carried out with and then without a standard three-layer surgical face mask. Adequate precautions were taken to prevent the spread of COVID-19 during the tests. Distance covered during the 6MWT was the primary outcome measure. The secondary outcome measures …
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