Body mass index and weight change are associated with mortality in chronic kidney disease: A retrospective cohort study using a Japanese medical claims database

医学 重量变化 体质指数 危险系数 队列 回顾性队列研究 数据库 肾脏疾病 内科学 减肥 死亡率 队列研究 优势比 肥胖 置信区间 计算机科学
作者
Yuria Ishida,Keisuke Maeda,Kenta Murotani,Akio Shimizu,Junko Ueshima,Ayano Nagano,Norihiro Sonoi,Tatsuro Inoue,Naoharu Mori
出处
期刊:Nutrition [Elsevier BV]
卷期号:116: 112147-112147
标识
DOI:10.1016/j.nut.2023.112147
摘要

This study aimed to investigate body mass index (BMI) and rate of weight change associated with adverse outcomes in Asian patients with chronic kidney disease.A retrospective cohort study was performed between April 2014 and June 2022 using the administrative claims database compiled by the Japan Medical Data Center. Patients were defined as individuals with comorbidities with chronic kidney disease stages 3 to 5 on admission and were aged ≥40 y with BMI at admission and BMI information from a previous admission 3 to 12 mo earlier. Restricted cubic spline analysis and thin-plate smoothed spline analysis were performed.A total of 10 802 individuals were analyzed. The mean age was 74.6 ± 11.3 y, number of men was 7175 (66.4%), and 2115 (19.6%) deaths were recorded. Smoothed splines for BMI found that low BMI was associated with high hazard ratio (HR) (BMI = 18.5 kg/m2; HR = 1.3 [1.2-1.4]). Smoothed splines of weight change found higher HR with increasing rate of weight change for both weight gain and loss (weight change rate = -10%; HR = 1.4 [1.3-1.5]; weight change rate = 10%; HR = 1.2 [1.1-1.3]). In thin-plate smoothed spline analysis, the U-curve had a higher odds ratio as BMI decreased in patients with or without dialysis and as the degree of weight change increased.We found trends in BMI and rate of weight change associated with mortality in Asian patients with chronic kidney disease.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
来瓶可乐完成签到,获得积分10
刚刚
YamDaamCaa应助冷静初彤采纳,获得50
1秒前
三岁居居发布了新的文献求助10
1秒前
123发布了新的文献求助10
1秒前
77完成签到,获得积分20
1秒前
1秒前
科研通AI2S应助ZY采纳,获得10
1秒前
科研通AI5应助平常的半凡采纳,获得10
1秒前
2秒前
2秒前
掌门完成签到,获得积分10
3秒前
风登楼发布了新的文献求助10
3秒前
左丘曼冬完成签到,获得积分10
4秒前
小罗黑的发布了新的文献求助10
5秒前
5秒前
香蕉觅云应助asbefore采纳,获得10
5秒前
Danboard发布了新的文献求助10
5秒前
5秒前
zzjjyy完成签到,获得积分10
6秒前
6秒前
鸢梓尔发布了新的文献求助10
6秒前
7秒前
7秒前
7秒前
Unfair完成签到,获得积分10
7秒前
Savannah发布了新的文献求助10
8秒前
高大梦琪发布了新的文献求助10
8秒前
在水一方应助王倩采纳,获得10
9秒前
hala安胖胖完成签到,获得积分10
9秒前
9秒前
天天快乐应助多情的飞绿采纳,获得10
9秒前
顾矜应助非凡梦采纳,获得10
9秒前
10秒前
i羽翼深蓝i完成签到,获得积分10
10秒前
Yolo发布了新的文献求助10
11秒前
赘婿应助专一的映容采纳,获得10
11秒前
123发布了新的文献求助10
12秒前
ting发布了新的文献求助10
12秒前
听南发布了新的文献求助10
12秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3970240
求助须知:如何正确求助?哪些是违规求助? 3514997
关于积分的说明 11176725
捐赠科研通 3250268
什么是DOI,文献DOI怎么找? 1795244
邀请新用户注册赠送积分活动 875725
科研通“疑难数据库(出版商)”最低求助积分说明 805004