Identification of GABAergic subpopulations in the lateral hypothalamus for home-driven behaviors in mice

Home information profoundly influences behavioral states in both humans and animals. However, how "home" is represented in the brain and its role in driving diverse related behaviors remain elusive. Here, we demonstrate that home bedding contains sufficient home information to modulate affective behaviors, including aversion responses, defensive aggression, and mating behaviors. These varied responses to home information are mediated by gama-aminobutyric acid (GABA)ergic neurons in the lateral hypothalamus (LH