Adolescent and adult differences in major depression symptom profiles

萧条(经济学) 心理学 精神科 临床心理学 医学 宏观经济学 经济
作者
Frances Rice,Lucy Riglin,Tessa Lomax,Emily Souter,Rachel Potter,Daniel J. Smıth,Ajay K Thapar,Ajay K Thapar
出处
期刊:Journal of Affective Disorders [Elsevier]
卷期号:243: 175-181 被引量:247
标识
DOI:10.1016/j.jad.2018.09.015
摘要

Depression is the leading global cause of disability and often begins in adolescence. The genetic architecture and treatment response profiles for adults and adolescents differ even though identical criteria are used to diagnose depression across different age groups. There is no clear consensus on how these groups differ in their symptom profiles.Using data from a two-generation family study, we compared the presentation of DSM-IV depressive symptoms in adolescents and adults with MDD (Major Depressive Disorder). We also compared DSM-IV depressive symptom counts using latent class analysis.Vegetative symptoms (appetite and weight change, loss of energy and insomnia) were more common in adolescent MDD than adult MDD. Anhedonia/loss of interest and concentration problems were more common in adults with MDD. When using latent class analysis to look at depressive symptoms, a vegetative symptom profile was also seen in adolescent depression only.Adults and adolescents were recruited in different ways. Adolescent cases were more likely to be first-onset while adult cases were recurrences. It was not possible to examine how recurrence affected adolescent depression symptom profiles.Differences in how depression presents in adolescents and adults may be consistent with different pathophysiological mechanisms. For adolescents, we found that vegetative/physical disturbances were common (loss of energy, changes in weight, appetite and sleep changes). For adults, anhedonia/loss of interest and concentration difficulties were more common.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
科目三应助李会琳采纳,获得10
刚刚
章鱼哥完成签到,获得积分10
1秒前
1秒前
1秒前
1秒前
miracle发布了新的文献求助10
2秒前
Will完成签到,获得积分10
2秒前
xjcy应助Wmin采纳,获得10
3秒前
烟花应助RY文献下载采纳,获得10
3秒前
OJM发布了新的文献求助20
4秒前
领导范儿应助嗒嗒嗒薇采纳,获得10
4秒前
LMDD发布了新的文献求助10
5秒前
6秒前
稳重的若雁应助打工人采纳,获得10
6秒前
蜜CC发布了新的文献求助10
7秒前
完美世界应助Vegccc采纳,获得10
7秒前
希望天下0贩的0应助td采纳,获得10
7秒前
yl完成签到,获得积分10
7秒前
9秒前
cookie完成签到,获得积分10
10秒前
mingjie发布了新的文献求助10
11秒前
隐形曼青应助飘逸的雪萍采纳,获得10
11秒前
华仔应助Aprial采纳,获得10
12秒前
12秒前
14秒前
14秒前
wsqg123发布了新的文献求助10
15秒前
善学以致用应助lingVing瑜采纳,获得10
15秒前
LMDD完成签到,获得积分10
16秒前
17秒前
华贞完成签到,获得积分10
18秒前
cola完成签到 ,获得积分10
19秒前
云枝发布了新的文献求助30
19秒前
19秒前
小白发布了新的文献求助10
19秒前
td发布了新的文献求助10
21秒前
21秒前
科研小天才完成签到,获得积分10
23秒前
24秒前
清玖完成签到,获得积分10
24秒前
高分求助中
Smart but Scattered: The Revolutionary Executive Skills Approach to Helping Kids Reach Their Potential (第二版) 1000
PraxisRatgeber: Mantiden: Faszinierende Lauerjäger 700
The Heath Anthology of American Literature: Early Nineteenth Century 1800 - 1865 Vol. B 500
A new species of Velataspis (Hemiptera Coccoidea Diaspididae) from tea in Assam 500
Machine Learning for Polymer Informatics 500
2024 Medicinal Chemistry Reviews 480
Women in Power in Post-Communist Parliaments 450
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3222736
求助须知:如何正确求助?哪些是违规求助? 2871510
关于积分的说明 8175845
捐赠科研通 2538464
什么是DOI,文献DOI怎么找? 1370613
科研通“疑难数据库(出版商)”最低求助积分说明 645818
邀请新用户注册赠送积分活动 619700