External validation of the Khorana score for the prediction of venous thromboembolism in cancer patients: A systematic review and meta-analysis

Venous thromboembolism is the leading cause of death in cancer patients, second only to tumor progression. The Khorana score is recommended by clinical guidelines for identifying ambulatory cancer patients at high risk of venous thromboembolism during chemotherapy. However, its predictive performance is debated among cancer patients.