材料科学
微流控
电介质
介电谱
微波食品加热
色散(光学)
光电子学
表面改性
共面波导
生物分析
光谱学
分析化学(期刊)
电容感应
分析物
极高频率
产量(工程)
纳米技术
化学
光学
色谱法
计算机科学
电极
电信
物理
物理化学
量子力学
电化学
操作系统
冶金
作者
G. R. Facer,Daniel A. Notterman,Lydia L. Sohn
摘要
We report developing coplanar waveguide devices which can perform dielectric spectroscopy on biological samples within a microfluidic channel or well. Since coupling to the fluid sample is capacitive, no surface functionalization or chemical sample preparation are required. Data on cell suspensions and solutions of proteins and nucleic acids spanning the frequency range from 40 Hz to 26.5 GHz are presented. Low-frequency data are well explained using a simple dispersion model. At microwave frequencies, the devices yield reproducible and distinguishable spectral responses for hemoglobin solution and live E. coli.
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