碳酸酐酶
锌
碳酸酐酶Ⅱ
化学
基因亚型
荧光
酶
细胞
生物化学
分子
细胞培养
生物物理学
生物
有机化学
基因
物理
量子力学
遗传学
作者
Radhika Mehta,Munaum H. Qureshi,Meredith Purchal,Sylvester M. Greer,Shanzhong Gong,Chinh Q. Ngo,Emily L. Que
摘要
We report the synthesis and application of a small molecule probe for carbonic anhydrase (CA) to track holo-CA in cell lysates and live-cell models of zinc dyshomeostasis. The probe displays a 12-fold increase in fluorescence upon binding to bovine CA and also responds to human CA isoforms.
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