DNA糖基化酶
炎症
氧化应激
DNA修复
DNA损伤
DNA
疾病
免疫学
生物
基底切除修复术
癌症研究
医学
生物化学
病理
作者
Abdullahi Samaila,Rusliza Basir,Mukhtar Gambo Lawal,Razif Abas,Maizaton Atmadini Abdullah,Roslaini Abd Majid,Norshariza Nordin,Mohd Khairi Hussain,Nur Izah Ab Razak,Yoke Keong Yong,Basiru Aliyu
标识
DOI：10.1080/08923973.2024.2391471
摘要
Inflammatory diseases are influenced by oxidative stress. Oxidatively damaged 8-oxoG in DNA is linked to inflammation. The enzyme OGG1 is responsible for repairing the damaged base in the DNA which is linked to pro-inflammatory signaling and severe inflammation. This study aims to explore the potential of targeting OGG1 as a therapeutic strategy in inflammatory disease conditions.
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