炎症体
细胞内
钾通道
化学
钾
流出
脂多糖
生物物理学
分子生物学
生物
生物化学
内分泌学
受体
有机化学
作者
C.N. Immanuel,Bin Teng,Brittany E. Dong,Elizabeth M. Gordon,Charlean Luellen,Benjamin Lopez,Jeffrey N. Harding,Stephania A. Cormier,Elizabeth Fitzpatrick,Andreas Schwingshackl,Christopher M. Waters
出处
期刊:American Journal of Physiology-lung Cellular and Molecular Physiology
[American Physiological Society]
日期:2024-01-22
卷期号:326 (3): L367-L376
被引量:1
标识
DOI:10.1152/ajplung.00313.2023
摘要
Because of the importance of potassium efflux in inflammasome activation, we investigated the role of the two-pore potassium (K2P) channel TREK-1 in macrophage inflammasome activity. Using primary alveolar macrophages (AMs) and bone marrow-derived macrophages (BMDMs) from wild-type (wt) and
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