膀胱切除术
医学
尿路改道
膀胱癌
淋巴结切除术
适应
阶段(地层学)
协议(科学)
造口(药)
外科
普通外科
癌症
内科学
病理
人文学科
古生物学
替代医学
哲学
生物
作者
Vincent D'Andrea,Kevin Melnick,Kendrick Yim,John Ernandez,Nnamdi Onochie,Timothy N. Clinton,Graeme S. Steele,Mark A. Preston,Adam S. Kibel,Matthew Mossanen
摘要
Radical cystectomy (RC) is an integral part of the management of patients with advanced-stage bladder cancer. This major oncologic operation is prone to complications resulting in morbidity and mortality. We analyzed the critical steps of open RC, performed an evidence-based review of these steps, and discussed our experience and approach. We conducted a literature review of the open RC technique, identified the critical steps that consistently appeared across different sources, and organized these steps into a framework. PubMed was queried with the critical steps as keywords for relevant articles published from 1 January 2013 to 1 August 2023. We utilized this query to conduct a systematic review of the literature using the outcomes of overall survival and 90-day complication rate. We developed the “Summary for the 10 Critical Operative Steps of Radical Cystectomy”, a concise guide to the approach to open RC. When available, an evidence-based analysis of each critical step was performed. We also included additional components of cystectomy optimization such as pre-habilitation in the preoperative phase, standard versus extended lymphadenectomy, the vaginal-sparing approach to female radical cystectomy, patient-reported outcomes following urinary diversion, the use of a mesh for stoma formation, and the use of the ERAS protocol for postoperative care. An evidence-based assessment of RC may help provide valuable information to optimize surgical techniques and patient outcomes.
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