Synthetic Methods for Multiply Substituted Butadiene-Containing Building Blocks

Conjugated organic systems have attracted much attention because new materials and functional structures can be expected from them. 2,4-Dienes mono- and disubstituted with electrophiles at the 1- and 1,6-positions, respectively, containing a butadienyl-conjugated skeleton and one or two terminal functional groups that can be manipulated, represent one of the most useful building units for the preparation of both cyclic and linear conjugated compounds. This account summarizes the synthetic methods available for multiply substituted butadiene-containing mono- or bis-electrophiles.