微型反应器
凝聚
纳米技术
模块化设计
化学
化学工程
材料科学
计算机科学
催化作用
有机化学
色谱法
操作系统
工程类
作者
Jianbo Liu,Liangfei Tian,Yan Qiao,Shaohong Zhou,Avinash J. Patil,Kemin Wang,Mei Li,Stephen Mann
标识
DOI:10.1002/anie.201916481
摘要
Immobilization of compartmentalized microscale objects in 3D hydrogels provides a step towards the modular assembly of soft functional materials with tunable architectures and distributed functionalities. Herein, we report the use of a combination of micro-compartmentalization, immobilization, and modularization to fabricate and assemble hydrogel-based microreactor assemblies comprising millions of functionalized polysaccharide-polynucleotide coacervate droplets. The heterogeneous hydrogels can be structurally fused by interfacial crosslinking and coupled as input and output modules to implement a UV-induced photocatalytic/peroxidation nanoparticle/DNAzyme reaction cascade that generates a spatiotemporal fluorescence read-out depending on the droplet number density, intensity of photoenergization, and chemical flux. Our approach offers a route to heterogeneous hydrogels with endogenous reactivity and reconfigurable architecture, and provides a step towards the development of soft modular materials with programmable functionality.
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