达帕格列嗪
医学
射血分数
心力衰竭
糖尿病
2型糖尿病
心脏病学
内科学
内分泌学
作者
John J.V. McMurray,Scott D. Solomon,Silvio E. Inzucchi,Lars Køber,Mikhail Kosiborod,Felipe A. Martínez,Piotr Ponikowski,Marc S. Sabatine,Inder S. Anand,Jan Bělohlávek,Michael Böhm,Chern‐En Chiang,Vijay Chopra,Rudolf A. de Boer,Akshay S. Desai,Mirta Díez,Jarosław Dróżdż,Andrej Dukát,Junbo Ge,Jonathan G. Howlett
标识
DOI：10.1056/nejmoa1911303
摘要
In patients with type 2 diabetes, inhibitors of sodium–glucose cotransporter 2 (SGLT2) reduce the risk of a first hospitalization for heart failure, possibly through glucose-independent mechanisms. More data are needed regarding the effects of SGLT2 inhibitors in patients with established heart failure and a reduced ejection fraction, regardless of the presence or absence of type 2 diabetes.
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