发病机制
非酒精性脂肪性肝炎
医学
非酒精性脂肪肝
肝细胞癌
薄壁组织
脂肪性肝炎
脂肪肝
内科学
肝病
疾病
病理
生物
癌症研究
肝星状细胞
肝硬化
作者
Tingting Zheng,R Li,Peng Tan,Mengping Huang,Bo Qian,H Chen,Wei Fu
标识
DOI:10.3760/cma.j.cn501113-20200301-00080
摘要
Non-alcoholic steatohepatitis (NASH) is an important link for the progression of metabolic-related fatty liver disease to end-stage liver disease such as cirrhosis and hepatocellular carcinoma, which seriously endangers human health. NASH pathogenesis is complex, and involves the interaction between hepatic parenchymal and non-parenchymal cells (NPCs), sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, and so on. Herein, the relevant research progress of NPCs in the pathogenesis of NASH is reviewed in order to further understand the role of NPCs in NASH.
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