Implementation of an online thermal imaging to study the effect of process parameters of roller compactor

丝带 压实 材料科学 热的 过程(计算) 复合材料 计算机科学 物理 气象学 操作系统
作者
Chalak Omar,Michael J. Hounslow,Agba D. Salman
出处
期刊:Drug Delivery and Translational Research [Springer Nature]
卷期号:8 (6): 1604-1614 被引量:4
标识
DOI:10.1007/s13346-018-0493-9
摘要

During roller compaction, not only the properties of the primary powder affect the product quality but also the process parameters. Any change in the process parameters during roller compaction will result in changing the properties of the ribbon. In this study, the temperature of the ribbon during production was monitored online using a thermal camera. The information from the thermal camera was used to explain the differences in ribbon properties at varying process parameters. Lactose powder was used as a primary powder, and ribbons were produced at different process parameters. The surface temperature of the ribbon during production was found to increase with increasing both the gap between the two rollers and the roller speed. This was attributed to the screw feeder speed, which increased to feed additional powder as required to adjust to the change in process parameters. Increasing the roller gap resulted in wider ribbons and decreased the percentage of fines in the product, which was a signature of better powder distribution across the roller width. The results were also supported by the uniform temperature distribution recorded across the ribbon width. It was found that increasing the roller speed during roller compaction decreased the width of the ribbon while increasing the percentage of fines in the product. The feeder screw speed was found to have a similar effect as the roller gap.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
2秒前
筱潇应助四夕采纳,获得10
2秒前
4秒前
高大美发布了新的文献求助20
4秒前
charitial发布了新的文献求助10
7秒前
Flame关注了科研通微信公众号
7秒前
五指鸭完成签到,获得积分10
8秒前
8秒前
回来完成签到,获得积分10
10秒前
11秒前
11秒前
Dreamsli发布了新的文献求助10
11秒前
11秒前
子不语完成签到 ,获得积分10
14秒前
14秒前
科目三应助zzz采纳,获得10
15秒前
18秒前
18秒前
19秒前
李国民完成签到,获得积分20
20秒前
李国民发布了新的文献求助10
24秒前
llzuo发布了新的文献求助10
25秒前
懒洋洋大王完成签到,获得积分20
25秒前
墨尘发布了新的文献求助50
25秒前
研友_VZG7GZ应助汤圆软软软采纳,获得10
27秒前
我是老大应助勤奋曼雁采纳,获得10
28秒前
29秒前
伊一完成签到,获得积分10
30秒前
31秒前
丘比特应助勤奋的南松采纳,获得10
33秒前
Vespa发布了新的文献求助10
33秒前
CipherSage应助秋半雪采纳,获得10
34秒前
FashionBoy应助清蒸鱼吖采纳,获得10
36秒前
小肚肚发布了新的文献求助10
37秒前
Alex完成签到,获得积分10
37秒前
科文完成签到,获得积分10
38秒前
Sunny完成签到,获得积分10
38秒前
Duke_ethan完成签到,获得积分10
38秒前
爆米花应助Flame采纳,获得10
40秒前
41秒前
高分求助中
The late Devonian Standard Conodont Zonation 2000
Nickel superalloy market size, share, growth, trends, and forecast 2023-2030 2000
The Lali Section: An Excellent Reference Section for Upper - Devonian in South China 1500
Very-high-order BVD Schemes Using β-variable THINC Method 890
Mantiden: Faszinierende Lauerjäger Faszinierende Lauerjäger 800
PraxisRatgeber: Mantiden: Faszinierende Lauerjäger 800
Saponins and sapogenins. IX. Saponins and sapogenins of Luffa aegyptica mill seeds (black variety) 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3260219
求助须知:如何正确求助?哪些是违规求助? 2901451
关于积分的说明 8315734
捐赠科研通 2571024
什么是DOI,文献DOI怎么找? 1396784
科研通“疑难数据库(出版商)”最低求助积分说明 653580
邀请新用户注册赠送积分活动 631997