Baseline findings in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study.

圆锥角膜 角膜曲率计 医学 视力 纵向研究 眼科 生活质量(医疗保健) 角膜地形图 隐形眼镜 角膜 病理 护理部
作者
Karla Zadnik,Joseph T. Barr,Timothy B. Edrington,Donald F. Everett,Mary Jameson,Timothy T. McMahon,Julie A. Shin,John L Sterling,Heidi Wagner,Mae O. Gordon
出处
期刊:PubMed 卷期号:39 (13): 2537-46 被引量:507
链接
标识
摘要

To describe the baseline findings in patients enrolled in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study.This is a longitudinal observational study of 1209 patients with keratoconus enrolled at 16 clinical centers. Its main outcome measures are corneal scarring, visual acuity, keratometry, and quality of life.The CLEK Study patients had a mean age of 39.29+/-10.90 years with moderate to severe disease, assessed by a keratometric-based criterion (95.4% of patients had steep keratometric readings of at least 45 D) and relatively good visual acuity (77.9% had best corrected visual acuity of at least 20/40 in both eyes). Sixty-five percent of the patients wore rigid gas-permeable contact lens, and most of those (73%) reported that their lenses were comfortable. Only 13.5% of patients reported a family history of keratoconus. None reported serious systemic diseases that had been previously reported to be associated with keratoconus. Many (53%) reported a history of atopy. Fifty-three percent had corneal scarring in one or both eyes.Baseline findings suggest that keratoconus is not associated with increased risk of connective tissue disease and that most patients in the CLEK Study sample represent mild to moderate keratoconus. Additional follow-up of at least 3 years will provide new information about the progression of keratoconus, identify factors associated with progression, and assess its impact on quality of life.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
1秒前
rubbick完成签到,获得积分10
1秒前
圆满组合发布了新的文献求助10
1秒前
大秀子完成签到,获得积分10
2秒前
2秒前
Mr.Su完成签到 ,获得积分10
2秒前
3秒前
优雅烨伟完成签到,获得积分10
3秒前
水水的很安心完成签到,获得积分10
4秒前
hgsd完成签到,获得积分10
5秒前
柳叶刀小猪应助SunGuangkai采纳,获得30
6秒前
6秒前
Lucas应助mz采纳,获得10
6秒前
愉悦发布了新的文献求助10
7秒前
领导范儿应助雷霆万钧采纳,获得10
8秒前
陈迹发布了新的文献求助10
9秒前
xfyxxh发布了新的文献求助10
9秒前
咸鱼发布了新的文献求助20
10秒前
Glowing完成签到,获得积分10
12秒前
13秒前
义气的牛青完成签到,获得积分10
13秒前
13秒前
雨er发布了新的文献求助10
15秒前
深情安青应助淡定的天抒采纳,获得10
18秒前
莉亚发布了新的文献求助30
19秒前
19秒前
Chaiyuan完成签到 ,获得积分10
22秒前
22秒前
星辰大海应助yyyy采纳,获得10
23秒前
23秒前
拓小八发布了新的文献求助10
23秒前
852应助水水的很安心采纳,获得10
24秒前
Aynuyoah2024发布了新的文献求助10
24秒前
充电宝应助hony采纳,获得10
27秒前
ding应助栉风沐雨采纳,获得10
27秒前
Owen应助儒雅的不愁采纳,获得10
29秒前
31秒前
31秒前
重要的念文完成签到,获得积分10
31秒前
高分求助中
Licensing Deals in Pharmaceuticals 2019-2024 3000
Cognitive Paradigms in Knowledge Organisation 2000
Effect of reactor temperature on FCC yield 2000
How Maoism Was Made: Reconstructing China, 1949-1965 800
Introduction to Spectroscopic Ellipsometry of Thin Film Materials Instrumentation, Data Analysis, and Applications 600
Promoting women's entrepreneurship in developing countries: the case of the world's largest women-owned community-based enterprise 500
Shining Light on the Dark Side of Personality 400
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3309624
求助须知:如何正确求助?哪些是违规求助? 2942923
关于积分的说明 8511679
捐赠科研通 2618018
什么是DOI,文献DOI怎么找? 1430760
科研通“疑难数据库(出版商)”最低求助积分说明 664249
邀请新用户注册赠送积分活动 649437