中性粒细胞胞外陷阱
医学
克罗恩病
炎症
细胞外
纤维化
免疫学
疾病
炎症性肠病
病理
细胞生物学
生物
作者
Gabriele Dragoni,Bo-Jun Ke,Lucia Picariello,Saeed Abdurahiman,E. Ceni,Francesca Biscu,Tommaso Mello,S. Polvani,Tommaso Innocenti,Valérie Spalart,Stefano Milani,André D’Hoore,Gabriele Bislenghi,Stefano Scaringi,Bram Verstockt,Gert De Hertogh,Kimberly Martinod,Andrea Galli,Gianluca Matteoli,Séverine Vermeire
出处
期刊：Journal of Crohn's and Colitis
[Oxford University Press]
日期：2024-08-10
被引量：1
标识
DOI：10.1093/ecco-jcc/jjae121
摘要
During early phases of inflammation, activated neutrophils extrude neutrophil extracellular traps (NETs) in a PAD4-dependent manner, aggravating tissue injury and remodelling. In this study, we investigated the potential pro-fibrotic properties and signalling of NETs in Crohn's disease (CD).
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