婴儿配方奶粉
生物
肠道菌群
粪便
蔷薇花
阿克曼西亚
食品科学
代谢物
生物化学
微生物学
乳酸菌
发酵
作者
Qingxue Chen,Qianlong Yin,Qinggang Xie,Sibo Liu,Zengwang Guo,Bailiang Li
出处
期刊:Food Chemistry
[Elsevier]
日期:2023-06-01
卷期号:410: 135413-135413
被引量:5
标识
DOI:10.1016/j.foodchem.2023.135413
摘要
The gut microbiota plays an evolutionarily conserved role in host metabolism, which is influenced by diet. Here, we investigated differences in shaping the gut microbiota and regulating metabolism in cow milk-based infant formula, goat milk-based infant formula, and mix milk-based infant formula compared with pasteurized human milk. 16S rRNA results showed that goat milk-based infant formula selectively increased the relative abundance of Blautia, Roseburia, Alistites and Muribaculum in the gut compared to other infant formulas. Metabolomics identification indicated that goat milk-based infant formula mainly emphasized bile acid biosynthesis, arachidonic acid metabolism and steroid biosynthesis metabolic pathways. Metabolites associated with these metabolic pathways were positively associated with increased microorganisms in goat milk-based infant formula, particularly Alistipes. Furthermore, we found a deficiency of Akkermansia abundance in three infant formula-fed compared to pasteurizedhuman milk-fed. This study presents new insights into the improvement and application of goat milk-based infant formulas in terms of intestinal microecology.
科研通智能强力驱动
Strongly Powered by AbleSci AI