细胞病变效应
病毒学
生物
抗体
中和抗体
效价
重叠感染
病毒
细胞培养
免疫学
遗传学
作者
Françoise Rey,Françoise Barré-Sinoussi,H. Schmidtmayerova,Jean-Claude Chermann
标识
DOI:10.1016/0166-0934(87)90008-5
摘要
An assay for determining neutralizing antibodies in sera from individuals infected with HIV was developed. This assay is based on an inhibition of the cytopathic effect observed after HIV superinfection of the HTLV-1-positive cell-line MT4. Only about 10% of asymptomatic seropositive donors exhibit a high titre over 1/500 up to 1/2000 while in 60% of sera, neutralizing antibodies were not detected. The assay reported here can also be used for the comparison of the biological properties of the different strains of HIV.
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