内质网
牙周纤维
牙周膜干细胞
细胞生物学
化学
癌症研究
生物
医学
牙科
生物化学
碱性磷酸酶
酶
作者
Xige Zhang,Y Z Wang,Jinjin Wang,Yang Zhang,Rui Li,Xiaoyu Wang,Xueling Ge,Qingyuan Ye,Jiyun Ji,Dongdong Fei,Qintao Wang
标识
DOI:10.1016/j.jare.2024.10.029
摘要
Decreased periodontal ligament stem cells (PDLSCs) stemness is a key factor in age-related alveolar bone loss. Endoplasmic reticulum (ER) stress is closely related to age-related diseases and the mesenchymal stem cell (MSC) stemness. However, the role of ER stress in regulating the stemness of senescent PDLSCs and its potential mechanism remain unclear.
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