再生(生物学)
纳米材料
组织工程
纳米技术
细胞分化
骨组织
干细胞
细胞生物学
材料科学
化学
生物医学工程
生物
医学
生物化学
基因
作者
Tianxu Zhang,Yang Gao,Weitong Cui,Yanjing Li,Dexuan Xiao,Ronghui Zhou
出处
期刊:Current stem cell research & therapy
[Bentham Science]
日期:2020-05-21
卷期号:16 (1): 36-47
被引量:14
标识
DOI:10.2174/1574888x15666200521083834
摘要
With the rapid development of nanotechnology, various nanomaterials have been applied to bone repair and regeneration. Due to the unique chemical, physical and mechanical properties, nanomaterials could promote stem cells osteogenic differentiation, which has great potentials in bone tissue engineering and exploiting nanomaterials-based bone regeneration strategies. In this review, we summarized current nanomaterials with osteo-induction ability, which could be potentially applied to bone tissue engineering. Meanwhile, the unique properties of these nanomaterials and their effects on stem cell osteogenic differentiation are also discussed. Furthermore, possible signaling pathways involved in the nanomaterials- induced cell osteogenic differentiation are also highlighted in this review.
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