Effects of astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers

We evaluated the effects of astaxanthin, a red carotenoid, on accommodation, critical flicker fusion (CFF), and pattern visual evoked potential (PVEP) in visual display terminal (VDT) workers. As controls, 13 non-VDT workers received no supplementation (Group A). Twenty-six VDT workers were randomized into 2 groups: Group B consisted of 13 subjects who received oral astaxanthin, 5 mg/day, for 4 weeks, and Group C consisted of 13 subjects who received an oral placebo, 5 mg/day, for 4 weeks. No significant difference in age was noted among the 3 groups. A double-masked study was designed in Groups B and C. Accommodation aqilitude in Group A was 3.72 1.5 diopters. Accommodation amplitudes (2.3 +- 1.4 and 2.2& 1 .O diopters) in Groups B and C before supplementation were significantiy (~~0.05) lower than in Group A. Accommodation amplitude (2.82 1.6 diopters) in Group B after astaxanthin treatment was significantly @