[Analysis of predictive factors affecting sentinel lymph node status in early breast cancer patients].

医学 前哨淋巴结 乳腺癌 淋巴 肿瘤科 转移 活检 组织病理学 内科学 淋巴结 癌症 病理
作者
Dechuang Jiao,Jianghua Qiao,Zhenduo Lu,Lian-fang Li,Hengwei Zhang,Hui Liu,Shude Cui,Haotian Lin
出处
期刊:Chinese journal of oncology 卷期号:36 (3): 198-201 被引量:2
标识
摘要

To investigate the predictive factors affecting sentinel lymph node status in early breast cancer patients.Clinicopathological data of 1 038 patients with early breast cancer, who underwent sentinel lymph node biopsy in Henan Tumor Hospital between July 2010 and August 2013, were reviewed. Logistic regression analysis was performed to identify the relevance of clinicopathological features with sentinel lymph node metastases.This group was consisted of 1 038 female patients with an average of 48.6 years. Positive sentinel lymph nodes were found in 22.9% (238/1 038) of the patients. The average number of sentinel lymph nodes removed by surgery was 3.8. Tumor size, tumor location, histopathology, ER/PR status and Ki-67 level were significantly correlated with SLN metastasis(P < 0.05 for all). All the above factors but Ki-67 level were significant independent predictors for SLN metastasis(P < 0.01 for all).Negative hormone receptor status, invasive cancer of non-specific histopathological type, tumor size >2 cm, and tumor location in the outer upper quadrat are independent predictive factors of sentinel lymph node metastasis in patients with early breast cancer.

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