The aim: To perform a morphometric assessment of the coronary arteries ostia by intravascular ultrasound with morphological evaluation among the Ukrainian population. Materials and methods: Intravascular images of the ostia of the right (48%) and left (52%) coronary arteries with the minimum diameter, maximum diameter, mean diameter and lumen area were analyzed. An intravascular ultrasound procedure was performed before percutaneous intervention. Results: A total of 25 IVUS examinations were collected from patients of both sexes and the same ages: 61,27±10,24 for males and females 68±5,83 (p=0.64).The left coronary artery (LCA) ostium assessment was performed in 13 (52%) cases: 8 men and 5 women (32% and 20%, respectively). The right coronary artery (RCA) ostium assessment was performed in 12 (48%) cases: 7 men and 5 women (28% and 20%, respectively). The maximal diameter of the coronary artery ostia was higher in men (5.95±0.66mm) than in women (4.82±0.34mm) (p<0.0001). In men, the maximal diameter of the RCA was higher than in the LCA (6.4±0.40mm and 5.56±0.60mm, respectively). The same differences were found in the mean diameter and lumen area (p<0.05). In women, the minimum diameter, mean diameter, maximum diameter and lumen area of the RCA were higher than LCA but without statistically signi#cant di"erences. The anatomic precondition explains the observed changes in echogenicity. Conclusions: IVUS analysis shows signi#cantly higher parameters of the minimum diameter, mean diameter, maximum diameter and lumen area in men than in women among the Ukrainian population. Therefore, morphological evaluation is crucial in the interpretation of intracoronary images.