医学
三阴性乳腺癌
彭布罗利珠单抗
乳腺癌
化疗
内科学
肿瘤科
病态的
完全响应
癌症
免疫疗法
作者
Peter Schmid,Javier Cortés,Lajos Pusztai,Heather L. McArthur,Sherko Kümmel,Jonas Bergh,Carsten Denkert,Yeon Hee Park,Rina Hui,Nadia Harbeck,Masato Takahashi,Theodoros Foukakis,Peter A. Fasching,Fátima Cardoso,Michael Untch,Liyi Jia,Vassiliki Karantza,Jing Zhao,Gursel Aktan,Rebecca Dent
标识
DOI:10.1056/nejmoa1910549
摘要
Among patients with early triple-negative breast cancer, the percentage with a pathological complete response was significantly higher among those who received pembrolizumab plus neoadjuvant chemotherapy than among those who received placebo plus neoadjuvant chemotherapy. (Funded by Merck Sharp & Dohme [a subsidiary of Merck]; KEYNOTE-522 ClinicalTrials.gov number, NCT03036488.).
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