医学
淋巴血管侵犯
淋巴结切除术
辅助治疗
子宫内膜癌
癌
淋巴结
内科学
肿瘤科
癌症
外科
妇科
转移
作者
Işın Üreyen,Hilal Ilgın,Taner Turan,Tolga Taşçı,Alper Karalök,Nurettin Boran,Ahmet Özfuttu,Gökhan Tulunay
标识
DOI:10.3109/01443615.2014.958441
摘要
Analysis of the surgicopathological characteristics and clinical follow-up of patients with undifferentiated uterine carcinoma (UUC) was conducted. A total of 18 cases operated between January 1993 and December 2013 were included. Among 1,690 patients with endometrial cancer, 18 patients (1.1%) had UUC. Lymph node involvement was detected in 70.6%; depth of myometrial invasion was ≥ 0.5 in 55.6%; lymphovascular space invasion was detected in 99.3%; cervical stromal invasion was positive in 27.8%; omental and adnexal involvement were detected in 11.8% and 38.9%, respectively. The median follow-up time of the 12 patients evaluated in the survival analysis was 66 months. In the follow-up period, recurrence or progression during adjuvant therapy were observed in four patients (33.3%) and two patients (16.6%) died of the disease. UUC manifests as an aggressive tumour. In conclusion, a high rate of survival could be achieved with complete staging surgery, including an extensive lymphadenectomy with the contribution of adjuvant therapy.
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