Antimicrobial resistance: a threat to global health

Antimicrobial resistance (AMR) presents a widespread, complex threat to global health and universal health coverage.1,2 Internationally, an estimated 700 000 deaths are attributed to AMR annually,3 with a projected economic impact of US$100 trillion by 2050.4 Worldwide, the burden of infectious diseases is increasing, particularly in low-income and middle-income countries (LMICs)5 and susceptible populations.6 The effectiveness of treatment for these infections, and the sustainability of health systems globally, are severely threatened by AMR.