医学
子宫输卵管造影术
怀孕
不育
回顾性队列研究
产科
妇科
妊娠率
外科
遗传学
生物
作者
Sarah Maheux‐Lacroix,C Bergeron,Lynne Moore,Marie-Ève Bergeron,J Lefèbvre,Iseult Grenier-Ouellette,Sylvie Dodin
标识
DOI:10.1016/j.jogc.2018.10.001
摘要
Abstract
Objective
This study sought to examine whether hysterosalpingosonography (sono-HSG) is as effective as hysterosalpingography (HSG) in facilitating conception by comparing pregnancy rates in the 6 months following the procedures. Methods
This retrospective noninferiority study (Canadian Task Force classification II-2) was conducted at a tertiary university centre. The investigators studied 440 consecutive eligible infertile women. Bilateral tubal occlusion, severe male infertility, and having undergone both procedures were exclusion criteria. Tubal testing, as part of the infertility workup, was performed by either sono-HSG or HSG. The primary outcome was pregnancy, defined as a positive fetal heartbeat on ultrasonographic examination, in the 6 months following the procedure. Results
A total of 57 pregnancies (26%) were observed in the HSG group and 33 (15%) in the sono-HSG group. Adjusted and non-adjusted relative risks of pregnancy in the 6 months following sono-HSG compared with HSG were 0.61 (95% CI 0.42–0.89) and 0.58 (95% CI 0.39–0.85). Adverse events were infrequent with both procedures (sono-HSG, 1%; HSG, 4%; P = 0.16). Conclusion
This study suggests that uterine flushing as performed during sono-HSG is not as effective as when performed during HSG to increase the chances of pregnancy, but further studies will be required because of bias related to the retrospective study design.
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