谷氨酰胺
精氨酸
谷氨酸
氨基酸
生物
腹泻
内科学
完全随机设计
内分泌学
生物化学
动物科学
医学
作者
David Rwbystanne Pereira da Silva,Leonardo Augusto Fonseca Pascoal,Aparecida da Costa Oliveira,Terezinha Domiciano Dantas Martins,José Humberto Vilar da Silva,Flávio Gomes Fernandes,Jonathan Mádson dos Santos Almeida
标识
DOI:10.1590/0001-3765202220201575
摘要
This study aimed to evaluate the supplementation of L-glutamine + glutamic acid and/or L-arginine on the productive performance, incidence of diarrhea, intestinal morphological of weaned piglets. Sixty-four 28-day-old weaned piglets were distributed in four treatments: DC - control diet; DG - glutamine diet (1% L-glutamine + glutamic acid); DA - arginine diet (1% L-arginine); and DGA - glutamine + arginine diet (0.5% L-glutamine + glutamic acid and 0.5% L-arginine) with eight replicates and two animals per experimental unit. The addition of 1% L-arginine to the piglet diet improved weight gain and feed conversion over 28 to 35 days of age. In the period of 28 to 49 days of age, supplementation with 1% L-glutamine + glutamic acid increased the animals' weight gain and reduced the incidence of diarrhea. Supplementation with amino acids in combination had a positive effect on the morphometric parameters of the intestinal mucosa compared to the control diet. Supplementation with 1% L-glutamine + glutamic acid increased the number of anti-PCNA+ cells and goblet cells. Taken together, our findings suggest that supplementation with L-glutamine + glutamic acid and L-arginine can improve the productive performance and enhance the integrity of the intestinal mucosa of weaned piglets.
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