基因分型
胎儿
医学
胎儿游离DNA
抗原
免疫学
抗体
产科
怀孕
血型抗原
产前诊断
基因型
生物
遗传学
基因
作者
Frederik Banch Clausen,C. Ellen van der Schoot
出处
期刊:PubMed
日期:2024-01-29
被引量:1
标识
DOI:10.2450/bloodtransfus.712
摘要
Noninvasive fetal blood group antigen genotyping serves as a diagnostic tool to predict the risk of hemolytic disease of the fetus and newborn in pregnancies of immunized women. In addition, fetal RHD genotyping is used as an antenatal screening to guide targeted use of immunoglobulin prophylaxis in non-immunized RhD negative, pregnant women. Based on testing of cell-free DNA extracted from maternal plasma, these noninvasive assays demonstrate high performance accuracies. Consequently, noninvasive fetal blood group antigen genotyping has become standard care in transfusion medicine.
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