医学
餐后
2型糖尿病
内分泌学
肥胖
内科学
激素
糖尿病
兴奋剂
减肥
胰岛素
受体
摘要
The buzz was palpable at the 2023 American Diabetes Association Scientific Sessions as multiple new nutrient-stimulated, hormone-based therapies for obesity and type 2 diabetes took center stage. Among these therapies, the triple–hormone-receptor agonist retatrutide — the subject of a phase 2 trial by Jastreboff et al., the results of which are published in this issue of the Journal1 — showed unprecedented efficacy in treating obesity, with 24% weight loss over 48 weeks. Hormonal responses to nutrient intake are key regulators of metabolism. The best known is insulin secretion in response to postprandial increases in levels of glucose or amino acids, . . .
科研通智能强力驱动
Strongly Powered by AbleSci AI