医学
布洛芬
吗啡
随机对照试验
可待因
急诊科
止痛药
麻醉
儿科
外科
精神科
药理学
出处
期刊:Evidence-based Medicine
[BMJ]
日期:2015-03-11
卷期号:20 (3): 105-105
被引量:2
标识
DOI:10.1136/ebmed-2015-110178
摘要
Commentary to: Poonai N, Bhullar G, Lin K, et al. Oral administration of morphine versus ibuprofen to manage postfracture pain in children: a randomized trial. CMAJ 2014;186:1358–63[OpenUrl][1][Abstract/FREE Full Text][2]. Untreated or undertreated pain in children can have short-term and long-term problems.1 ,2 For fractures in children, it is widely accepted that the most severe pain occurs in the first 48 h postinjury. Following recent warnings from Health Canada on the safety of codeine,3 ,4 there has been an increased use of morphine and anti-inflammatory medication for postfracture pain. This study was carried out to compare the efficacy of the morphine with ibuprofen for fracture pain in children. This randomised controlled trial was conducted in the paediatric emergency department at the Children's Hospital in London, Ontario. Children aged between 5 and17 years of age with a radiographically evident extremity fracture sustained in the preceding 24 h were invited … [1]: {openurl}?query=rft.jtitle%253DCMAJ%26rft_id%253Dinfo%253Adoi%252F10.1503%252Fcmaj.140907%26rft_id%253Dinfo%253Apmid%252F25349008%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=cmaj&resid=186/18/1358&atom=%2Febmed%2F20%2F3%2F105.atom
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