收缩性
心室
心脏病学
心力衰竭
内科学
材料科学
医学
生物医学工程
作者
Xuecheng Qu,Sijing Cheng,Ying Liu,Yiran Hu,Yizhu Shan,Ruizeng Luo,Sixian Weng,Hui Li,Niu Hong-xia,Min Gu,Yubo Fan,Bojing Shi,Zhuo Liu,Wei Hua,Zhou Li,Zhong Lin Wang
标识
DOI:10.1002/adma.202402457
摘要
Cardiovascular disease (CVD) remains the leading cause of death worldwide. Patients often fail to recognize the early signs of CVDs, which display irregularities in cardiac contractility and may ultimately lead to heart failure. Therefore, continuously monitoring the abnormal changes in cardiac contractility may represent a novel approach to long-term CVD surveillance. Here, a zero-power consumption and implantable bias-free cardiac monitoring capsule (BCMC) is introduced based on the triboelectric effect for cardiac contractility monitoring in situ. The output performance of BCMC is improved over 10 times with nanoparticle self-adsorption method. This device can be implanted into the right ventricle of swine using catheter intervention to detect the change of cardiac contractility and the corresponding CVDs. The physiological signals can be wirelessly transmitted to a mobile terminal for analysis through the acquisition and transmission module. This work contributes to a new option for precise monitoring and early diagnosis of CVDs.
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