医学
神经肌肉疾病
重症监护医学
肺功能测试
弱点
模式
物理医学与康复
疾病
物理疗法
外科
内科学
社会科学
社会学
作者
Eric Gartman,F. Dennis McCool
出处
期刊:Handbook of Clinical Neurology
日期:2022-01-01
卷期号:: 3-13
被引量:3
标识
DOI:10.1016/b978-0-323-91532-8.00007-0
摘要
Neuromuscular disorders frequently compromize pulmonary function and effective ventilation, and a thorough respiratory evaluation often can assist in diagnosis, risk assessment, and prognostication. Since many of these disorders can be progressive, serial assessments may be necessary to best define a trajectory of impairment or improvement with therapy. Patients with neuromuscular diseases may have few respiratory symptoms and limited signs of skeletal muscle weakness, but can have significant respiratory muscle weakness. A single testing modality may fail to elucidate true respiratory compromise, and often a combination of tests is recommended to fully evaluate these patients. Common tests performed in this population include measurement of flow rates, lung volumes, maximal pressures, and airways resistance. This review covers the major respiratory testing modalities available in the evaluation of these patients, emphasizing both the benefits and shortcomings of each approach. The majority of parameters are available in a standard pulmonary laboratory (flows, volumes, static pressures), although referral to a specialized center may be necessary to conclusively evaluate a given patient.
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