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Predictive Factors of Intestinal Ischaemia in Adhesive Small Bowel Obstruction

医学 优势比 内科学 置信区间 缺血 背景(考古学) 降钙素原 剖腹手术 单变量分析 肠梗阻 外科 胃肠病学 多元分析 败血症 古生物学 生物
作者
Xiangmin Li,Mei Tian,Yulin Liu,Yongbo Zhang,Jingbo Chen
出处
期刊:JCPSP. Journal of the College of Physicians & Surgeons Pakistan [College of Physicians and Surgeons Pakistan]
卷期号:34 (02): 146-150
标识
DOI:10.29271/jcpsp.2024.02.146
摘要

To identify the predictive factors of intestinal ischaemia in adhesive small bowel obstruction (ASBO) and develop an intestinal ischaemia risk score.Observational study. Place and Duration of the Study: Department of General Surgery, Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, China, from January 2017 to February 2022.ASBO was determined by findings at laparotomy. The assessment of small bowel's viability was conducted through surgical inspection and subsequent histological examination of the surgical specimen. Univariate and multivariate analyses were conducted to ascertain the risk factors associated with intestinal ischaemia.In total, 79 patients were included. Factors entered into multivariate analysis associated with intestinal ischaemia were; rebound tenderness (odds ratio (OR): 7.8, 95% confidence interval (CI):1.7-35.3; p=0.008), procalcitonin (PCT) >0.5 ng/mL (OR: 11.7, 95% CI: 2.3-58.1; p=0.003), and reduced bowel wall enhancement on computerised tomography (CT) scan (OR: 12.2, 95% CI:2.4-61.5; p=0.003). Among patients with 0, 1, 2, and 3 factors, the rate of intestinal ischaemia increased from 0% to 49%, 72%, and 100%, respectively. According to the number of risk factors, the area under the receiver operating characteristic curve for the determination of intestinal ischaemia was 0.848 (95% CI: 0.764-0.932).Rebound tenderness, PCT levels >0.5 ng/mL, and reduced bowel wall enhancement are risk factors of intestinal ischemic injury that require surgery within the context of ASBO. These factors need to be closely monitored that could assist clinicians in avoiding unnecessary laparotomies and selecting patients eligible for surgery.Intestinal obstruction, Ischaemia, Adhesions.

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