Organocatalyzed diastereoselective cyclization of β-alkyl nitroolefins with alkylidene malononitriles: new approach to azetidine nitrones and isoxazoles

An efficient, organocatalytic, diastereoselective, atom-economic domino method has been established for the rapid access to a wide breadth of highly strained azetidine nitrones with a tetra-substituted chiral carbon center in...