微粉化
药物输送
超临界流体
粒径
材料科学
粒子(生态学)
喷雾干燥
工艺工程
溶解度
粒度分布
纳米技术
化学工程
工程类
化学
有机化学
地质学
海洋学
作者
Niraj Kale,Ketaki Shinde,Sonam Bendre,Suhit Gilda
出处
期刊:Asian Journal of Pharmaceutical Research
[Diva Enterprises Private Limited]
日期:2022-11-22
卷期号:: 349-358
标识
DOI:10.52711/2231-5691.2022.00055
摘要
Particle engineering is a technique that involves the customization of particles in order to get desired properties of the pharmaceutical products. The use of particle engineering is in obtaining optimum particle size and particle size distribution and getting particles of desired size. The other aspects of the particle engineering involves the morphological changes of the drug substances. The particle engineering involves improvement of physicochemical properties such as solubility, stability, improved bioavailability and formulation of novel drug delivery systems such as pulmonary drug delivery system. This article includes various techniques used for the particle engineering such as Micronization, Spray drying, high pressure homogenization, Supercritical fluid technology and freeze drying. Article also covers the different uses of particle engineering in pharmaceutical industry.
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