化学
杂原子
位阻效应
硅烷
二硅烷
锂(药物)
计算化学
药物化学
有机化学
硅烷
戒指(化学)
医学
内分泌学
作者
Joachim Heinicke,Steffen Mantey
标识
DOI:10.1002/(sici)1098-1071(1998)9:3<311::aid-hc6>3.0.co;2-c
摘要
The reductive coupling of chlorotris(diorganylamino)silanes 1 with chlorotrimethylsilane by the action oflithium in THF provides for steric reasons, an easy access to unsymmetrical aminosubstituted disilanes (R2N)3Si-SiMe3 3. Similarly, cross-coupling to give pentakis(diethylamino)disilane 4 is observed between 1a and bis(diethylamino)chloro-hydridosilane 2a on treatment with lithium. In reactions of the less bulky bis(diorganylamino)chlorohy-dridosilanes 2 with ClSiMe3 and Li, however, thesymmetrical coupling is preferred and affords SiH-functional substituted (R2N)32HSi-SiH(NR2)2 5. Aminosubstituted disilanes 3–5 are useful starting materials for modification of disilanes or syntheses ofsilicon heterocycles via generation and trapping of aminosilylenes, as exemplified by diethylaminosilacyclopent-3-ene 6a. © 1998 John Wiley & Sons, Inc. Heteroatom Chem 9:311–316, 1998
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