小RNA
糖尿病性心肌病
医学
心肌病
生物信息学
药理学
计算生物学
内科学
心力衰竭
生物
遗传学
基因
作者
Priyanka Mathur,Sharad Saxena,Bhawna Saxena,Vibha Rani
出处
期刊:Cardiovascular and Hematological Agents in Medicinal Chemistry
[Bentham Science]
日期:2024-01-24
卷期号:22 (3): 298-307
被引量:1
标识
DOI:10.2174/0118715257265947231129074526
摘要
: MicroRNAs have emerged as an important regulator of post-transcriptional gene expression studied extensively in many cancers, fetal development, and cardiovascular diseases. Their endogenous nature and easy manipulation have made them potential diagnostic and therapeutic molecules. Diseases with complex pathophysiology such as Diabetic Cardiomyopathy display symptoms at a late stage when the risk of heart failure has become very high. Therefore, the utilization of microRNAs as a tool to study pathophysiology and device-sustainable treatments for DCM could be considered. The present review focuses on the mechanistic insights of diabetic cardiomyopathy and the potential role of microRNAs.
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