化学
芳基
配体(生物化学)
组合化学
反应条件
偶联反应
药物化学
有机化学
催化作用
生物化学
受体
烷基
出处
期刊:Synlett
[Georg Thieme Verlag KG]
日期:2023-02-09
卷期号:34 (12): 1395-1398
被引量:5
标识
DOI:10.1055/s-0042-1751414
摘要
Abstract Two picolinamide ligands were found to have significant accelerating effect to classical Rosenmund–von Braun reaction, making the coupling of (hetero)aryl bromides with CuCN occur at 100–120 °C with good to excellent yields in most cases. A large number of functional groups and heterocycles were tolerated under these conditions, thereby providing a convenient and reliable approach for diverse synthesis of aryl nitriles.
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