Comparative evaluation of broth microdilution and gradient diffusion methods in Burkholderia cepacia complex susceptibility testing: implications of transitioning to ECV-based interpretation

Although the adoption of ECVs improved CA for some agents, MIC-level discrepancies between Etest and BMD persisted. Species-specific resistance patterns and the low concordance with clinical outcomes (40.9%) highlight the limitations of AST alone in guiding BCC treatment decisions.