医学
四分位间距
流行病学
队列
回顾性队列研究
公共卫生
病历
队列研究
儿科
内科学
生存分析
人类免疫缺陷病毒(HIV)
免疫学
病理
作者
Cristiane Marcos Soares Dias Ferreira,Isabel Cristina Gonçalves Leite
标识
DOI:10.31744/einstein_journal/2022ao6474
摘要
To characterize the epidemiological profile of patients aged 50 years or older diagnosed as HIV/AIDS, in a Specialized Service of the Public Health System.A retrospective cohort study using secondary data from medical records in the period 2014 to 2018. Sociodemographic and clinical characteristics, and features related to treatment adherence were organized in a database. Quantitative variables were expressed as mean (or median) ± standard deviation (or interquartile range), and categorical variables expressed as number and percentage of patients. The Kaplan-Meier method was applied to assess the probability of overall specific survival.Of the 241 initially eligible patients, 149 patients were evaluated, registering 19 deaths in the studied period. There was a predominance of males aged 50-59 years, with severe immunodeficiency upon admission (29.7%), and with a CD4+ T lymphocyte count below 200 cells in 62 (46.3%) of patients. Elderly people aged 61 or over were more adherent. There was an increase in the CD4+ T lymphocyte count by an average of 139.63 in the first 6 months, and 50.51 from the first 6 months to 12 months of follow-up, with an average increase in the first 12 months of 157.63 cells. Specific overall survival in the period was 85%.Patients older than 50 years had an immune response and no viral load detection in the 12-month period, deserving further studies to improve survival.
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