Triflumuron (TFM) is a benzoyl phenyl urea insecticide belonging to the class of IGRs.TFM is widely used around the world to increase crop yield by protecting them from damage caused by insects.TFM works by inhibiting the synthesis of chitin, an essential part of the insect cuticle, making it susceptible to pathogens and deformities.However, studies revealing its toxicity and its mode of action in mammalian systems remain very limited.The aim of this review is to better inform the community about the impact of TFM on crops, the environment, and human beings by summarizing its toxic effects.