DNA
纳米技术
DNA纳米技术
逻辑门
计算机科学
纳米结构
癌症
计算生物学
医学
生物
材料科学
算法
内科学
遗传学
作者
Shiyi Bi,Rong Yang,Ju Huangxian,Ying Liu
标识
DOI:10.1002/cbic.202400754
摘要
DNA logic gates with dynamic nanostructures have made a profound impact on cancer diagnosis and treatment. Through programming the dynamic structure changes of DNA nanodevices, precise molecular recognition with signal amplification and smart therapeutic strategies have been reported. This enhances the specificity and sensitivity of cancer theranostics, and improves diagnosis precision and treatment outcomes. This review explores the basic components of dynamic DNA nanostructures and corresponding DNA logic gates, as well as their applications for cancer diagnosis and therapies. The dynamic DNA nanostructures would contribute to cancer early detection and personalized treatment.
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