锌指
无名指区
无名指
博士手指
序列同源性
同源(生物学)
戒指(化学)
锌
LIM域
蛋白质功能
计算生物学
生物
蛋白质结构
序列(生物学)
化学
肽序列
细胞生物学
遗传学
生物化学
氨基酸
基因
转录因子
有机化学
作者
Andrew J. Saurin,Katherine L. B. Borden,Michael N. Boddy,Paul S. Freemont
标识
DOI:10.1016/s0968-0004(96)80017-x
摘要
The RING finger is a zinc-binding domain that is found in proteins from plants to humans, but whose function remains largely enigmatic. The domain itself is distinct from other zinc-finger motifs in terms of sequence homology, zinc-ligation scheme and three-dimensional structure. It appears that the RING is involved in mediating protein-protein interactions and in some cases multi-protein complexes, which might depend on the presence of other proteins and/or domains.
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