立体化学
内酯
真菌
化学
二维核磁共振波谱
碳-13核磁共振
发酵
有机化学
生物
植物
作者
Min Wang,Gui-Yang Xia,Yongxin Liang,Huan Xia,Peng-Cheng Lin,Sheng Lin
标识
DOI:10.1080/10286020.2024.2335254
摘要
A new 14-membered resorcylic acid lactone (RAL14), chaetolactone A (1), along with three known ones (2-4), was obtained from the fermentation of the soil-derived fungus Chaetosphaeronema sp. SSJZ001. Their structures were established based on extensive spectroscopic data analyses (UV, IR, HRESIMS, 1D, and 2D NMR),13C NMR chemical shifts calculations coupled with the DP4+ probability method, theoretical calculations of ECD spectra, as well as X-ray diffraction analysis. All compounds were evaluated for their cytotoxic effects against A549, HO-8910, and MCF-7 cell lines.
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