The synthesis of 2-phenyl-5H-imidazo[2,1-a] [2,4]benzodiazepines

Abstract A one step synthesis of 2‐phenyl‐5 H ‐irnidazo[2,1‐ a ][2,4]benzodiazepines ( 4 ) from 2‐(2‐imidazolyl)benzophenones ( 3 ) is reported. Oximation and reduction of the benzophenone, 3a led to the benzhydrylamine derivative 7 which was cyclized to differently substituted 6,7‐di‐hydroimidazo[2,1‐ a ][2,4]benzodiazepines depending on the reactant chosen.