Opioid sparing multimodal analgesia enhances surgery recovery and reduces chronic postoperative surgical pain

MMA was one important component in enhanced recovery after surgery (ERAS). MMA combines opioid and non-opioid medication through different routes and mechanisms of action and covers the whole perioperative period, thus minimizing opioid use and preventing chronic post-surgical pain (CPSP). There was consensus that MMA could avoid opioid overdose originated from poor acute post-surgical pain control with opioid-dominant pain management in the era of opioid epidemic.